American Pathology and Oncology Research

Biography

Biography: Saran lotfollahzadeh

Abstract

Disorders of Sex Development is a childhood and infantile anomaly that affect not only the somatic growth; but also leading to stress and anxiety among parents who are seeking optimal treatments. Accordingly in this study the surgical outcomes in patients with Disorders of Sex Development in Mofid Children’s Hospital from 2001 to 2014 were determined.

In this case series study 72 consecutive children with Disorders of Sex Development in Mofid Children’s Hospital from 2001 to 2014 were enrolled and followed in a regular manner. Data were gathered by existing medical documents and were recorded in prepared checklist. The surgical outcomes were assessed with interview and clinical examination after announcement by hospital. The success and complication rate were determined by group of surgeons and compared according to other variables. In the current study we have evaluated seventy two patients; 55 (76.38%) affected by Congenital Adrenal Hyperplasia, thirteen (18.05%) by Testicular Feminization , 2 (2.7%) by OvoTesticular Disorder and two case (2.7%) by Mixed Gonadal Dysgenesis (MGD). Most common type of applied surgery was Clitroplasty, Genitoplasty and Pullthrough Vaginoplasty (table1). Fifty nine patients (81.9%) had no surgical complications. All patients had good conditions at discharge and no mortality was registered. Three cases of  Testicular Feminization (4.2%) Who Underwent pulltrough colovaginoplasty were  married. According to our findings, surgical outcomes in cases of Disorders of Sex Development are relatively good and satisfactory. However long-term follow-up study is required to determine the final outcomes especially for marital and sexual issues.

Table 1- Surgical Techniques